The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling).
Set FIG function to
D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)
1/9/2007
SvetaG
Set FIG function to
Glyoxylate reductase (1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81)
1/9/2007
SvetaG
Nunez MF, Pellicer MT, Badia J, Aguilar J, Baldoma L. 2001 Biochemical characterization of the 2-ketoacid reductases encoded by ycdW and yiaE genes in Escherichia coli. Biochem J, 354(Pt 3):707-15
1/9/2007
SvetaG
Set FIG function to
Glyoxylate reductase (1.1.1.79) / Hydroxypyruvate reductase (EC 1.1.1.81)
1/11/2007
SvetaG
Set FIG function to
Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81)
3/7/2007
SvetaG
Set FIG function to
Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81) ; 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-)
4/23/2007
RossO
Set function to
Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-)
This feature is part of a subsystem
In Glycolate, glyoxylate interconversions its role is Glyoxylate reductase (EC 1.1.1.26) and Glyoxylate reductase (EC 1.1.1.79) and Hydroxypyruvate reductase (EC 1.1.1.81).
In Photorespiration (oxidative C2 cycle) its role is Hydroxypyruvate reductase (EC 1.1.1.81). However, this subsystem has been classified as not being functional in this organism.
In Glycolate, glyoxylate interconversions its role is Glyoxylate reductase (EC 1.1.1.26) and Glyoxylate reductase (EC 1.1.1.79) and Hydroxypyruvate reductase (EC 1.1.1.81).
Reasons for Current Assignment
The encoded protein plays multiple roles which are implemented by distinct domains within the
feature. The roles are "Glyoxylate reductase (EC 1.1.1.79)", "Glyoxylate reductase (EC 1.1.1.26)"
and "Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC
1.1.1.215) (EC 1.1.1.-)". The protein occurs in 2 subsystems: "D-gluconate and ketogluconates
metabolism", and "Glycolate, glyoxylate interconversions". In "Glycolate, glyoxylate
interconversions", it appears to play a functional role that we have not associated with any other
gene. The function of genes having the same functional roles have been described in Homo sapiens
(10484776, 10524214, 10679197). This is a homologous protein which implements the same function.
Compare Regions
The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.
Topic revision: r6 - 02 Mar 2009 - 22:06:54 - Bruce Parrello
